INTRODUCTION Understanding how cancer adapts to treatment has long been a mystery for doctors and scientists alike. While many people are familiar with the idea that cancer can become “resistant” to chemotherapy over time, what’s often less clear is how this happens so quickly—sometimes within just a few days of starting treatment. Conventional wisdom has … Leggi tutto Biophysical Modulation of Chromatin Architecture as a Mechanism to Enhance Chemotherapy Efficacy: A Transcriptional Plasticity Approach to Overcoming Tumor Adaptation