Monkeypox can lead to death with encephalitis or inflammation of the brain

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Spain reported on Saturday a second death from monkeypox with more than 120 individuals now hospitalized due to disease severity. Both the fatalities and those hospitalized were mainly young men.

Globally more than 1,638 individuals are now hospitalized from monkeypox due to severe conditions. Both Monkeypox deaths in Spain were due to encephalitis or inflammation of the brain and a number who are currently hospitalized have also developed encephalitis

As of Sunday, 0720hrs (New York), more than 23,238 individuals have been infected with the monkeypox virus outside the African continent and the number is rising exponentially for a variety of reasons ie…the virus has a long incubation period is between 5 to 21 days and also due to the fact a number of individuals are asymptomatic coupled with the fact that viral clearance can be prolonged in many.

StateSort by state in no orderNumber of CasesSort by number of cases in descending order
New York1345
California799
Illinois419
Florida373
Texas351
Georgia351
District Of Columbia218
Pennsylvania125
Washington120
New Jersey118
Maryland117
Massachusetts116
Virginia76
Oregon58
North Carolina53
Colorado53
Arizona50
Indiana49
Louisiana38
Minnesota33
Connecticut33
Michigan28
Utah27
Tennessee26
Ohio23
Rhode Island19
South Carolina16
Alabama16
Puerto Rico14
Nevada14
Wisconsin13
Nebraska10
Iowa10
Hawaii10
Oklahoma9
New Hampshire9
Missouri9
Kentucky8
New Mexico7
Idaho4
Delaware4
Arkansas4
West Virginia3
Mississippi3
South Dakota1
North Dakota1
Maine1
Kansas1
Alaska1

The United States is now the leading country with the most reported cases at roughly 5,189 and local experts that the figures will still rise drastically as many test results are still not out yet.

LocationSort by location in no orderCasesSort by cases in descending orderCategorySort by category in no order
United States Of America4,906Has not historically reported monkeypox
Spain4,298Has not historically reported monkeypox
Germany2,595Has not historically reported monkeypox
United Kingdom2,546Has not historically reported monkeypox
France1,955Has not historically reported monkeypox
Brazil978Has not historically reported monkeypox
Netherlands879Has not historically reported monkeypox
Canada803Has not historically reported monkeypox
Portugal633Has not historically reported monkeypox
Italy479Has not historically reported monkeypox
Belgium393Has not historically reported monkeypox
Peru269Has not historically reported monkeypox
Switzerland264Has not historically reported monkeypox
Democratic Republic Of The Congo163Has historically reported monkeypox
Nigeria133Has historically reported monkeypox
Israel133Has not historically reported monkeypox
Austria124Has not historically reported monkeypox
Sweden88Has not historically reported monkeypox
Ireland85Has not historically reported monkeypox
Denmark81Has not historically reported monkeypox
Poland59Has not historically reported monkeypox
Mexico59Has not historically reported monkeypox
Norway51Has not historically reported monkeypox
Chile45Has not historically reported monkeypox
Australia45Has not historically reported monkeypox
Hungary37Has not historically reported monkeypox
Slovenia33Has not historically reported monkeypox
Greece32Has not historically reported monkeypox
Ghana30Has historically reported monkeypox
Luxembourg28Has not historically reported monkeypox
Romania21Has not historically reported monkeypox
Argentina20Has not historically reported monkeypox
Czechia19Has not historically reported monkeypox
Malta17Has not historically reported monkeypox
Finland17Has not historically reported monkeypox
United Arab Emirates16Has not historically reported monkeypox
Croatia12Has not historically reported monkeypox
Colombia12Has not historically reported monkeypox
Singapore11Has not historically reported monkeypox
Serbia10Has not historically reported monkeypox
Iceland9Has not historically reported monkeypox
Central African Republic8Has historically reported monkeypox
Cameroon7Has historically reported monkeypox
Slovakia6Has not historically reported monkeypox
Estonia6Has not historically reported monkeypox
Gibraltar5Has not historically reported monkeypox
Lebanon4Has not historically reported monkeypox
India4Has not historically reported monkeypox
Bulgaria4Has not historically reported monkeypox
South Africa3Has not historically reported monkeypox
Saudi Arabia3Has not historically reported monkeypox
Latvia3Has not historically reported monkeypox
Ecuador3Has not historically reported monkeypox
Dominican Republic3Has not historically reported monkeypox
Costa Rica3Has not historically reported monkeypox
Benin3Has not historically reported monkeypox
Andorra3Has not historically reported monkeypox
Thailand2Has not historically reported monkeypox
Taiwan2Has not historically reported monkeypox
Republic Of The Congo2Has historically reported monkeypox
Qatar2Has not historically reported monkeypox
New Zealand2Has not historically reported monkeypox
Japan2Has not historically reported monkeypox
Jamaica2Has not historically reported monkeypox
Venezuela1Has not historically reported monkeypox
Turkey1Has not historically reported monkeypox
South Korea1Has not historically reported monkeypox
Russia1Has not historically reported monkeypox
Philippines1Has not historically reported monkeypox
Panama1Has not historically reported monkeypox
New Caledonia1Has not historically reported monkeypox
Morocco1Has not historically reported monkeypox
Martinique1Has not historically reported monkeypox
Liberia1Has historically reported monkeypox
Georgia1Has not historically reported monkeypox
Bosnia And Herzegovina1Has not historically reported monkeypox
Bermuda1Has not historically reported monkeypox
Barbados1Has not historically reported monkeypox
Bahamas1

What is concerning American and European researchers is the fact that hospitalizations due tomonkeypox disease severity is now rising globally and indicating a speculation that the current monkeypox strains are still mutating rapidly and changing its pathogenesis. Many of the infected are now developing encephalitis or brain inflammationa and the monkeypox virus could be mutating and becoming more neuropathogenic!
 
Already genomic sequencings being uploaded from various countries on the GISAID platform is showing that the monkeypox virus is still mutating rapidly.
 
The monkeypox deaths outside Africa come one week after the World Health Organization declared the monkeypox outbreak a global health emergency.
 
Dr Catherine Smallwood, Senior Emergency Officer at WHO Europe told “The notification of deaths due to monkeypox does not change our assessment of the outbreak in Europe. We know that although the disease is self-limiting in most cases, monkeypox can cause severe complications. With the continued spread of monkeypox in Europe, we will expect to see more deaths. Our goal needs to be on interrupting transmission quickly in Europe and stopping this outbreak.”

Another concerning development is that many experts are now doubting the efficacy of the current monkeypox vaccines being used as case reports are now emerging that some previously vaccinated individuals are still contracting the disease with no difference in symptoms and manifestations. Some of these cases reports from Spain, United Kingdom and the United States are expected to be published in this coming week.

reference data : https://www.cdc.gov/poxvirus/monkeypox/response/2022/world-map.html

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