Researchers report the number of children infected with COVID-19 is far more extensive than being reported

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The number of children infected with the coronavirus is far more extensive than what is currently reported — a hidden detail that could vastly underestimate the demand on health care systems and pediatric intensive care units (PICUs).

A new study published in the “Journal of Public Health Management and Practice” from the University of South Florida (USF) and the Women’s Institute for Independent Social Enquiry (WiiSE), estimates that for each child who requires intensive care for COVID-19, there are 2,381 children infected with the virus.

This calculation follows a report from the Chinese Center for Disease Control and Prevention regarding its clinical study of over 2,100 children in China with COVID-19.

According to the North American registry, Virtual PICU Systems, 74 children in the U.S. were admitted to PICUs between March 18 and April 6, signaling an additional 176,190 children were likely infected during this timeframe.

Children younger than 2 accounted for 30 percent of the cases, 24 percent were ages 2 to 11 and 46 percent of the PICU cases were children between ages 12 and 17.

Researchers say that if as many as 25 percent of the U.S. population becomes infected with the coronavirus before the end of 2020, 50,000 children with severe illness will need to be hospitalized, with 5,400 of them critically ill and requiring mechanical ventilation.

Clinical reports indicate the average length of stay for pediatric COVID-19 is 14 days. According to a national survey aimed to evaluate the U.S. pediatric critical care capacity and published in “Critical Care Medicine,” there are approximately 5,100 PICU beds in the U.S.

This is a graph from the study
Projected numbers of children aged 0 to 17 years in the United States who will require hospitalization for COVID-19 during 2020. The image is credited to USF.

“Although the risk of severe illness from COVID-19 is lower in pediatric cases than adults, hospitals should be prepared and have the proper equipment and staffing levels to deal with a potential influx of younger patients,” said author Jason Salemi, associate professor of epidemiology in the USF College of Public Health.

“Government officials and policy makers should understand the likelihood of capacity challenges, which underscores the importance of effective mitigation strategies such as frequent and thorough handwashing and persisted social distancing measures.”

Pediatric coronavirus is highly complex, as many hospitals are prohibiting visitors in order to implement social distancing and quarantine protocols.

A caretaker may also be infected, which would require logistical and infection control accommodations that place an additional strain on hospital resources. Upon hospital discharge, young children may be unable to independently comply with home infection control and self-isolation recommendations.

Researchers point out the infection rate will be much higher for children in low-income families with parents in blue-collar and service jobs, which preclude the option of working from home.

There’s also an increased risk to children who live in urban public housing projects due to the close proximity of housing units and small communal recreation and commons areas.

The study’s authors recommend all state health departments and the CDC begin reporting confirmed COVID-19 cases in age-specific tables, using the standard 5-year age groups for health surveillance and make the data publicly available.


Main Outcomes and Measures: 

Adjusted pediatric severity proportions and adjusted pediatric criticality proportions were derived from clinical and spatiotemporal modeling studies of the COVID-19 epidemic in China for the period January-February 2020.

Estimates of total children infected with SARS-CoV-2 in the United States through April 6, 2020, were calculated using US pediatric intensive care unit (PICU) cases and the adjusted pediatric criticality proportion.

Projected numbers of severely and critically ill children with COVID-19 were derived by applying the adjusted severity and criticality proportions to US population data, under several scenarios of cumulative pediatric infection proportion (CPIP).

Results: 

By April 6, 2020, there were 74 children who had been reported admitted to PICUs in 19 states, reflecting an estimated 176 190 children nationwide infected with SARS-CoV-2 (52 381 infants and toddlers younger than 2 years, 42 857 children aged 2-11 years, and 80 952 children aged 12-17 years).

Under a CPIP scenario of 5%, there would be 3.7 million children infected with SARS-CoV-2, 9907 severely ill children requiring hospitalization, and 1086 critically ill children requiring PICU admission.

Under a CPIP scenario of 50%, 10 865 children would require PICU admission, 99 073 would require hospitalization for severe pneumonia, and 37.0 million would be infected with SARS-CoV-2.


Source:
USF

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