Monthly Archives: Giugno 2023
Vitamin D3 Modulates NLRP3 Inflammasome Activation in SARS-CoV-2 Infection: A Potential Therapeutic Approach for...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, leading to coronavirus disease 2019 (COVID-19), has emerged as a global crisis with severe inflammatory responses primarily affecting the respiratory system.
The excessive release of proinflammatory...
The Role of PSEN1 Mutations in Alzheimer’s Disease
Alzheimer's disease (AD) is a devastating neurodegenerative disorder and the sixth leading cause of death in the United States. Despite its prevalence and impact, the exact cause of AD remains unknown.
Existing treatments for...
The Impact of Early Life Stress and Trauma on Immune System Aging: Implications for...
Early life experiences of stress and trauma have been extensively studied for their profound implications on health throughout adulthood. Research has shown that individuals who have experienced childhood trauma are at an increased risk...
Peruvoside – Covid-19: A Broad-Spectrum Antiviral Targeting Viral Factory Formation and GBF1 Phosphorylation in...
Peruvoside is a natural compound that belongs to the class of cardiac glycosides, which are substances that can affect the heart muscle and rhythm. Peruvoside is extracted from the plant Cascabela thevetia, also known...
Interactions Between SARS-CoV-2 and CYP3A4 Metabolism: Implications for Medication Management during COVID-19
SARS-CoV-2, the virus responsible for COVID-19, has caused a devastating global pandemic, resulting in the loss of millions of lives .
COVID-19 encompasses a wide spectrum of disease severity, ranging from asymptomatic or mild...
The Liver-Brain Axis and Peripheral Manifestations in Alzheimer’s Disease: Exploring New Perspectives
Alzheimer's disease (AD) is a neurodegenerative disorder that affects millions of people worldwide. It is characterized by progressive cognitive decline, memory loss, and behavioral changes.
The main pathological features of AD are the accumulation...
Esplorazione della modulazione attenzionale delle rappresentazioni neurali nella cognizione dei bambini
L'attenzione è un'abilità cognitiva cruciale che ci consente di concentrarci su informazioni rilevanti e ignorare le distrazioni. Tuttavia, l'attenzione si sviluppa lentamente nei bambini ed è influenzata da molti fattori, come l'età, la motivazione e...
Exploring Attentional Modulation of Neural Representations in Children’s Cognition
Attention is a crucial cognitive skill that allows us to focus on relevant information and ignore distractions. However, attention develops slowly in children and is influenced by many factors, such as age, motivation, and...
Unveiling the Inner Self: Causal Evidence Reveals Anterior Precuneus’ Role in Processing Bodily Self
In this blog post, I will summarize the main findings and implications of a recent study published in Neuron by Dian Lyu and colleagues, titled "Causal evidence for the processing of bodily self in...
Exploring the Link Between COVID-19 Vaccination and Neuroinflammatory Disorders: A Comprehensive Analysis of NMOSD...
Novel coronavirus disease (COVID-19) is a respiratory illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
It was first detected in Wuhan, China, in December 2019, and by March 2021, the World...
Personalized Alternative Therapies for Tinnitus: A Comprehensive Stud
Tinnitus, a condition characterized by the perception of ringing or buzzing sounds in the ears without any external source, is a symptom with a controversial origin.
Previous studies have suggested that tinnitus may be...
COVID-19: Nearly 100,000 More Deaths from Cardiovascular Disease Since the Start of the Pandemic...
Since the start of the COVID-19 pandemic, England has experienced a devastating increase in deaths related to cardiovascular disease.
According to a recent analysis published by the Office for Health Improvement and Disparities (OHID),...
Covid-19 can remain in the middle ear effusion (MEE) long after infection
In this blog post, we will review a recent case series published in the European Archives of Oto-Rhino-Laryngology by Zhang et al. (2023) on COVID-19-related secretory otitis media in the omicron era.
Middle ear...
Alterazioni dei globuli rossi nell’infezione pediatrica da SARS-CoV-2: implicazioni per la patologia della malattia...
La sindrome respiratoria acuta grave coronavirus 2 (SARS-CoV-2) ha causato la pandemia globale della malattia da coronavirus 2019 (COVID-19), che può portare a gravi insufficienza multiorgano e morte.
I meccanismi patologici alla base di COVID-19...
The Role of Dopamine in Pursuing Uncertain Rewards: Coping with Lack of Expected Reward
Rewards are often uncertain and not easily obtained. In the pursuit of uncertain rewards, it is crucial to understand how to maximize the chances of obtaining them.
Even in the face of disappointment resulting...