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Monthly Archives: Novembre 2023

The Potential of 1,5-Anhydro-D-Fructose in Mitigating Aging-Associated Brain Diseases

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5′-Adenosine monophosphate-activated protein kinase (AMPK) stands as a pivotal serine/threonine kinase, evolutionarily conserved to maintain cellular energy homeostasis. Its regulatory role spans across various physiological and metabolic processes, making it a crucial determinant in...

Rutan : svelare un nuovo paradigma antivirale contro COVID-19

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La pandemia globale della malattia da coronavirus (COVID-19) ha posto sfide senza precedenti alla salute pubblica e al benessere socioeconomico (1–3). La capacità del virus di manipolare i meccanismi di difesa cellulare e di eludere...

Rutan Resurgence: Unveiling a Novel Antiviral Paradigm Against COVID-19

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The global coronavirus disease (COVID-19) pandemic has posed unprecedented challenges to public health and socio-economic well-being (1–3). The virus's ability to manipulate cellular defense mechanisms and evade the interferon response has prompted intense research...

Exploring the Impact of Subjective Beliefs on Neuromodulation Treatment Outcomes

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In the realm of medical, neuroscience, psychology, and educational research, the efficacy of various treatments, including drugs, cognitive training, biofeedback, and neurostimulation, has been under rigorous scrutiny. However, the diverse findings in these fields...

Exploring Polydrug Use Among Individuals with Heroin Dependence: A Longitudinal Study on Cannabis Products

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Polydrug use, the concurrent use of multiple substances, is prevalent among individuals with opioid use disorders (OUD) and has been associated with worsened health outcomes (Compton et al., 2021). Cannabis, in particular, is frequently...

The Intriguing Role of CD300f Immune Receptor in Aging-Related Processes

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Aging is a complex and multifactorial process characterized by the gradual accumulation of molecular damage, leading to age-related frailty, disability, disease, and eventual mortality. Macrophages, essential components of the immune system, play crucial roles...

The Interplay of Human and Pet Personality Traits in the Dynamics of Attachment

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The profound bond between humans and their pets is a well-established aspect of the human experience, contributing positively to the welfare of both parties involved. The strength of this attachment bond, however, plays a...

Pinostrobin: un flavonoide multifunzionale con potenziali applicazioni terapeutiche

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Il pinostrobin (C16H14O4) è un composto flavonoide derivato da erbe tradizionali cinesi come le foglie di Carya cathayensis, Boesenbergia rotunda e propoli. Con un peso molecolare di 270,28 dalton, la pinostrobina presenta un'ampia gamma di effetti...

Neural Mechanisms of Emotional Eating: The Role of Lateral Hypothalamic Proenkephalin Neurons

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Emotional eating, characterized by the excessive consumption of comfort foods in response to negative emotional valence rather than physical hunger, has been a subject of scientific inquiry due to its impact on individuals exposed...

Pinostrobin: A Multifunctional Flavonoid with Potential Therapeutic Applications

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Pinostrobin (C16H14O4) is a flavonoid compound derived from traditional Chinese herbs such as Carya cathayensis leaves, Boesenbergia rotunda, and propolis. With a molecular weight of 270.28 daltons, pinostrobin exhibits a wide range of pharmacological...

Metabolic Dysfunction in Glial Cells: Unraveling the Complexities of Glaucoma Pathology

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Glaucoma, a leading cause of irreversible blindness globally, affects a staggering 80 million diagnosed patients, with an additional significant number undiagnosed. The hallmark of glaucoma is the progressive dysfunction and degeneration of retinal ganglion...

Understanding the Complex Dynamics of Cross-Species Transmission: A Comprehensive Analysis of SARS-CoV-2 and its...

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The global impact of the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has reached unprecedented levels. As of October 7, 2023, the World Health Organization (WHO) reported over...

The Complex Interaction Between Caffeine and Human Brain Plasticity

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Caffeine, a widely consumed psychostimulant, has long been recognized for its impact on adenosine receptors, particularly as a competitive antagonist of the A1 and A2A subtypes. The intricate interplay between caffeine and long-term potentiation...

The Enigma of Sexual Motivation: A Neurobiological Perspective

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An ancient Chinese proverb posits, "Without copulation, no population" (Malmnäs, 1973). Although not universally applicable, this maxim holds true for species with internal fertilization. This article explores the intricate relationship between copulation and reproduction,...

Decoding COVID-19’s Lethal Grasp on Young Lungs

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The COVID-19 pandemic has left an indelible mark on global public health, with far-reaching consequences that continue to affect various aspects of healthcare. Despite the official declaration of the pandemic's end, new cases of COVID-19...