Monthly Archives: Dicembre 2023
The Molecular Switch: Understanding SARS-CoV-2 Spike Protein’s Role in COVID-19
The emergence of the novel coronavirus, SARS-CoV-2, in late 2019 led to a global pandemic, causing widespread illness and death on an unprecedented scale...
Exploring the Role of Extracellular Vesicles in SARS-CoV-2 Reactivation and Transmission
SARS-CoV-2, identified as the causative agent of the 2019–2021 viral pneumonia outbreak, led to a wide range of clinical manifestations known as COVID-19. The...
Advancing Neuroinflammation-Directed Gene Therapy: Targeting Alzheimer’s Disease with Innovative Microglia Lipid Nanoparticles
Neurodegenerative disorders, particularly Alzheimer's disease (AD), are often associated with neuroinflammation, a condition that is increasingly the focus of research and clinical efforts due...
Revolutionizing AI Hardware: Bridging the Gap with Brain-Inspired Technologies
Artificial Intelligence (AI) is dramatically transforming industries, medicine, society, and education, heralding a new era of technological advancement. The core driver of this revolution...
Exploring the Role of Demyelination in Post-COVID Depression
The outbreak of COVID-19 caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in late 2019 rapidly escalated into a global pandemic. By...
Studio dei benefici cognitivi dell’estratto di Wasabi (Eutrema japonicum) (6-MSITC) negli anziani sani
Il declino cognitivo è un fenomeno ben consolidato associato all’invecchiamento, con gli anziani che spesso mostrano prestazioni cognitive inferiori rispetto alle loro controparti più...
Investigating the Cognitive Benefits of Wasabi (Eutrema japonicum) Extract (6-MSITC) in Healthy Older Adults
Cognitive decline is a well-established phenomenon associated with aging, with older adults often exhibiting lower cognitive performances compared to their younger counterparts . This...
The persistent impact of SARS-CoV2 on the brain
On May 5, 2023, the World Health Organization (WHO) officially declared the end to the COVID-19 pandemic. While this announcement marked a significant milestone,...
Advancements in Gene Therapy for Glaucoma: Targeting the Actin Cytoskeleton and Oxidative Stress
Glaucoma, a leading cause of global visual loss, affects approximately 80 million individuals worldwide . The disease involves progressive damage to the optic nerve...
The Intricate Role of α5β1 Integrin in SARS-CoV-2 Spike-Mediated Infection and COVID-19 Pathogenesis
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, employs angiotensin-converting enzyme 2 (ACE2) as its cell entry receptor, akin to...
The Antiviral Potential of Cobicistat and Ritonavir Against SARS-CoV-2 Variants and Other Human Coronaviruses
The ongoing pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has highlighted the urgent need for effective antiviral treatments. The Coronaviridae...
Exploring the Anti-Obesity Potential of Citrus sphaerocarpa Hexane Extract
Obesity, a complex medical condition stemming from an imbalance between calorie intake and expenditure, affects a staggering number of individuals globally . In 2016,...
COVID-19: the Emergence and Growth of JN.1 Variant in the United States
The landscape of the COVID-19 pandemic is ever-evolving, with new variants constantly emerging. One such variant that has recently come into focus is JN.1....
Long-Term Impact of SARS-CoV-2 Infection on Macrophages and Natural Killer Cells
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for the ongoing global COVID-19 pandemic, exhibits a complex interaction with the host immune...
Identification and Characterization of a Novel Echarate Virus Variant Causing Acute Febrile Illness in...
The genus Phlebovirus, belonging to the order Bunyavirales and family Phenuiviridae, comprises 66 species, globally distributed and transmitted by various vectors such as sandflies,...